Concept information
Preferred term
pattern recognition receptor
Definition(s)
- Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system. PRRs are germline-encoded host sensors, which detect molecules typical for the pathogens. They are proteins expressed, mainly, by cells of the innate immune system, such as dendritic cells, macrophages, monocytes, neutrophils and epithelial cells, to identify two classes of molecules: pathogen-associated molecular patterns (PAMPs), which are associated with microbial pathogens, and damage-associated molecular patterns (DAMPs), which are associated with components of host's cells that are released during cell damage or death. (Wikipedia)
Broader concept(s)
Narrower concept(s)
Synonym(s)
- pattern-recognition receptor
- PRR
Creator
- Patricia Fener
In other languages
-
French
-
récepteur de reconnaissance de pathogène
-
récepteur de reconnaissance de pathogènes
URI
http://data.loterre.fr/ark:/67375/C0X-CNB525MT-S
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