Concept information
Preferred term
infection-associated enhanced disease
Definition(s)
- Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication. Antiviral antibodies promote viral infection of target immune cells by exploiting the phagocytic FcγR or complement pathway. After interaction with the virus the antibody binds Fc receptors (FcR) expressed on certain immune cells or some of the complement proteins. (Wikipédia)
Broader concept(s)
Synonym(s)
- antibody-dependent enhancement
Creator
- Patricia Fener
In other languages
-
French
-
facilitation de l'infection par des anticorps
URI
http://data.loterre.fr/ark:/67375/C0X-GGJVKFJT-9
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