Concept information
Término preferido
Dactinomycin
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Tipo
-
mesh:Descriptor
Definición
- A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
Concepto genérico
etiqueta alternativa (skos)
- 1CC1JFE158
- 50-76-0 (Dactinomycin)
- Actinomycin D
- Meractinomycin
En otras lenguas
-
francés
-
1CC1JFE158
-
50-76-0 (Dactinomycin)
-
Actinomycin D
-
Actinomycine C1
-
Actinomycine D
URI
http://data.loterre.fr/ark:/67375/JVR-XNS27FG0-Z
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