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Langue des données

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Facteurs biologiques > Médiateurs de l'inflammation > Prostaglandines synthétiques > Prostaglandines E synthétiques > Rioprostil

... > Éicosanoïdes > Prostaglandines > Prostaglandines synthétiques > Prostaglandines E synthétiques > Rioprostil

... > Éicosanoïdes > Prostaglandines > Prostaglandines synthétiques > Prostaglandines E synthétiques > Rioprostil

Terme préférentiel

Rioprostil

Définition(s)

A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.

Concept(s) générique(s)

Prostaglandines E synthétiques

Synonyme(s)

77287-05-9 (Rioprostil)
7JL402PVQR
Prost-13-en-9-one, 1,11,16-trihydroxy-16-methyl-, (11alpha,13E)-

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Antiulcéreux

Traductions

Rioprostil

anglais
77287-05-9 (Rioprostil)
7JL402PVQR
Prost-13-en-9-one, 1,11,16-trihydroxy-16-methyl-, (11alpha,13E)-

URI

http://data.loterre.fr/ark:/67375/JVR/M0025346

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RDF/XML TURTLE JSON-LD Date de création 25/01/1991, dernière modif. 08/06/2015